Phenyl Mercuric Nitrate

Premium Antimicrobial Preservative for Ophthalmic Applications

Phenyl Mercuric Nitrate

Phenyl mercuric nitrate stands as a specialized organomercury compound that serves as a highly effective antimicrobial preservative in pharmaceutical formulations, particularly ophthalmic preparations. This fine chemical demonstrates exceptional preservative properties, making it an essential component for manufacturers developing eye care products that require robust microbial protection. As a trusted specialty chemical, phenyl mercuric nitrate offers pharmaceutical formulators a reliable solution for maintaining product sterility and extending shelf life in sensitive ophthalmic applications. At Heni, we manufacture and supply pharmaceutical-grade phenyl mercuric nitrate that meets stringent international quality standards. Our product serves as a critical preservative system for contact lens solutions, eye drops, and other ophthalmic preparations where maintaining sterility is paramount. The compound's unique molecular structure provides broad-spectrum antimicrobial activity while remaining compatible with delicate ocular formulations.

Key Features & Benefits

Pharmacopeial Compliance (IP, USP, BP, EP)
Pharmacopeial Compliance (IP, USP, BP, EP)

Ensures acceptance in regulated markets; provides assurance of purity, identity, and performance.

Pharmacopeial Compliance (IP, USP, BP, EP)
Antimicrobial Preservation
Antimicrobial Preservation

Effective in protecting ophthalmic formulations against bacterial and fungal contamination, especially important in multi‑dose containers.

Antimicrobial Preservation
Specialization for Ophthalmic Use
Specialization for Ophthalmic Use

Formulated to be compatible with eye care vehicles; attention paid to minimizing irritation risk and ensuring safety in ocular contact.

Specialization for Ophthalmic Use
Stability & Reliability
Stability & Reliability

Designed to maintain preservative efficacy over shelf life when stored properly; consistent batch‑to‑batch uniformity.

Stability & Reliability
Small Effective Dose
Small Effective Dose

Only minimal concentration required to achieve preservation, helping keep formulation integrity and minimizing potential adverse effects.

Small Effective Dose

Pharmaceutical Applications

Ophthalmic Solutions

Primarily used as a preservative in eye drops, artificial tears, and other liquid eye preparations to prevent microbial growth and preserve efficacy.

Contact Lens Solutions

Added to cleaning and storage solutions to maintain sterility and ensure user safety.

Ophthalmic Ointments

Provides long-lasting antimicrobial protection in semi-solid eye formulations without affecting consistency or application.

Pharmaceutical Manufacturing

Used in select drug formulations where its preservative properties outperform alternatives.

Certifications

Kosher Certified

Kosher Certified

By Star-K

FSSAI

FSSAI

Food Safety and Standards Authority of India

ISO 9001:2015

ISO 9001:2015

Quality Management Systems

GMP

GMP

Good Manufacturing Practices



Technical Specifications

Parameter Specification
Chemical Name Phenyl Mercuric Nitrate
CAS Number 55-68-5
Molecular Formula C₆H₅HgNO₃
Molecular Weight 339.70 g/mol
Appearance White to off-white crystalline powder
Solubility Slightly soluble in water, soluble in alcohol
Melting Point 176-180°C
Purity Between 62.5% to 64.0%
pH (1% aqueous solution) 5.5-7.5
Loss on Drying ≤ 1.0%
Storage Conditions Store in cool, dry place away from light
Shelf Life 36 months from date of manufacture

IP grade

USP grade

BP grade

EP grade

Safety & Handling Information 

Phenyl Mercuric Nitrate, while highly effective, is a mercury‑based compound and must be handled with care. Here are essential safety guidelines: 

  • Personal Protective Equipment (PPE) 
    Always use gloves, protective eyewear, lab coat or protective garments. Avoid direct skin contact and inhalation of dust. 
  • Work Environment 
    Use in well‑ventilated areas or under fume hoods. Prevent dust generation, maintain controlled exposure to avoid accumulation of mercury compounds. 
  • Storage Conditions 
    Store ZONqs‑113 in tightly sealed, light‑resistant containers. Keep in cool, dry places, away from moisture and excessive heat. Ensure containers are clearly labeled. 
  • Disposal Practices 
    Given its mercury content, waste must be disposed of according to applicable hazardous material regulations. Neutralization or specialized chemical waste routes may be required; do not dispose of as general waste. 
  • Regulatory Compliance 
    When formulating Phenyl Mercuric Nitrate for ophthalmic products, ensure the final product meets safety limits, labeling, and regulatory frameworks in target markets. Maintain Certificate of Analysis and safety documentation. 

Why Choose Heni Chemicals for Your Supply of ZONqs‑113 Phenyl Mercuric Nitrate? 

When selecting a supplier for an antimicrobial preservative such as Phenyl Mercuric Nitrate, the choice of partner matters. Here’s why Heni Chemicals is a compelling option: 

  • Brand & Product Trust: ZONqs‑113 is part of our specialized “ZONqs” line, trusted for pharmaceutical chemicals. 
  • Regulated Grade Assurance: Our product is officially catalogued as meeting IP, USP, BP, EP standards. You receive assurance of quality and regulatory alignment. 
  • Ophthalmic Application Expertise: Because the focus is specifically ophthalmic preparations, our product and documentation are optimized for those uses. 
  • Quality & Purity Control: Tight control over manufacturing steps and thorough analysis ensures high purity, consistency, and minimal impurities, crucial with mercury‑based compounds. 
  • Support & Documentation: We provide necessary documentation (COA, safety data sheet), support for regulatory filings, and product‑specific guidance for handling and use. 

Frequently Asked Questions

Yes, but with strict concentration limits and region-specific regulations. In many countries, including the US and EU, its use is limited to very low concentrations (e.g., ≤0.002%) and only in certain product types like multi-dose ophthalmic solutions. Always consult with your regulatory affairs team and refer to regional pharmacopeias.

As a mercury-based compound, Phenyl Mercuric Nitrate should be handled with appropriate PPE, fume hoods, and safety protocols. Waste disposal and environmental discharge must follow local hazardous waste regulations. Heni supplies a detailed MSDS and handling guidelines to support safe use.

Phenyl Mercuric Nitrate offers broad-spectrum antimicrobial protection at very low concentrations. While newer non-mercurial options exist (e.g., benzalkonium chloride, polyquaternium-1), PMN remains preferred in some legacy formulations for its long history of efficacy and stability, especially in sterile environments.

Yes, we offer flexible packaging solutions to meet specific customer requirements. This includes custom container sizes, specialized labeling, and packaging formats suitable for different manufacturing environments. Contact our sales team to discuss your specific packaging needs.

Each shipment includes a Certificate of Analysis confirming product specifications, Safety Data Sheet with handling and safety information, and Technical Data Sheet with detailed product information. Additional regulatory documentation can be provided upon request.